The targeting construct inserted into the translation start site in exon 1 an inducible cre recombinase gene (cre/ERT2), an IRES sequence, a Venus reporter gene and a FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:217489)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count