ENU mutagenesis induced an A to G transition at base pair 76,908,668 (v38) on chromosome 8, or base pair 9,408 in the GenBank genomic region NC_000074, corresponding to residue 432 in the NM_001083906 mRNA sequence in exon 2 of 9 total exons. The mutation results in an isoleucine (I) to valine (V) substitution at position 133 (I133V) in the encoded protein. (J:225269)