A loxP site and FRT flanked beta-geo cassette were inserted upstream of exon 2 and a loxP site was inserted downstream of exon 6 via homologous recombination. Flp mediated recombination removed the beta-geo cassette leaving exons 2-6 floxed. See http://www.taconic.com/8077 for more information. (J:216983)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count