A loxP site was inserted in intron 6 and an FRT and loxP flanked pgk-neo cassette was inserted in intron 7 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 7 floxed. (J:217087)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count