A neo cassette was inserted in the 5' region of exon 2 and 126 bp including a loxP site was inserted in the 3' region via homologous recombination. RT-PCR detected no change in mRNA expression of Enho or Dnaic1. Western blot analysis confirmed the absence of ENHO protein expression. (J:216870)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count