A neo cassette was inserted in the 5' region of exon 2 and 126 bp including a loxP site was inserted in the 3' region via homologous recombination. RT-PCR detected no change in mRNA expression of Enho or Dnaic1. Western blot analysis confirmed the absence of ENHO protein expression. (J:216870)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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