This allele from project Zfp422-7040J-M1223 was generated at The Jackson Laboratory by injecting Cas9 RNA and 2 guide sequences, CCACACTCATCACAGCAGTA and GTGGCCATTCGCTTCGACTC, which resulted in a 301 bp deletion beginning in exon 2 at Chromosome 6 negative strand position 116,626,917bp, CTCGGGCTTGAGTCGACGGA, and ending after ACCGGCGAGAAGCCCTACTGC at 116,626,617 bp (GRCm38/mm10) in exon 2. This mutation results in the deletion of 301 bp in exon 2 and results in an amino acid sequence change after residue 40 and early truncation 41 amino acids later. (J:188991)
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突变
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C57BL/6NJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
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hm: 纯合子
ht: 杂合子
cn: 条件基因型
cx: 复合型:涉及多基因组
tg: 转基因
ot: 其他:半合子、不确定...
(F): 雌性
(M): 雄性
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(#): 上标括号内为相关疾病数量
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