A loxP site was inserted upstream of exon 3 and a loxP site and FRT flanked puro cassette were inserted downstream of exon 4 via homologous recombination. Flp mediated recombination removed the puro cassette. (J:216490)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count