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The EGFP-cre/ERT2 (GCE) fragment with an SV40 poly adenylation site and neomycin resistance cassette were inserted immediately downstream of the translational initiation codon ATG. The knock-in construct interrupted coding sequence in exon 2 and placed the GCE gene under the control of the endogenouse regulatory sequences. Flp-mediated recombination removed the selection cassette. No expression of GFP was detected with fluorescence or using antibody to GFP. The fusion cre is expressed in intercalated duct cells of parotid gland and serous cells of sublingual gland. (J:229520)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
