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The chicken beta-actin (CAG) promoter, a loxP flanked STOP cassette, and human FGFR2 isoform IIIb cDNA with the kinase K660N domain activating mutation were inserted into the mouse collagen A1 locus. Upon cre-mediated recombination, the STOP cassette is excised promoting expression of the mutant FGFR2. (J:214230)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
