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The endogenous coding sequence was replaced by the sequence encoding amoino acids 1 through 333 of Mc4r followed by an IRES-tauGFP cassette for bicistronic expression. The ACNf neomycin selection cassette was self-excised by Cre recombination in the germline of the male chimera. (J:260975)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
