A 0.5 kb genomic region including exon 6 was flanked with loxP sites and a floxed neo cassette was inserted via homologous recombination. Cre mediated recombination removed the neo cassette. (J:216027)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count