A genomic region spanning the entire open reading frame (exons 2-6) was replaced with a construct including an NLS-lacZ, viral T2A sequence, histone 2B, Venus reporter gene, and SV40-pA and a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:215971)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x 129S6/SvEvTac)F1
Targeted
Insertion, Intragenic deletion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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