The targeting vector contains a loxP-flanked neomycin cassette and sequence encoding Enhanced Green Fluorescent Protein was used to disrupt the coding region of the Ccr7 gene. Transient transfection with a cre-expressing plasmid DNA removed the selection cassette. (J:223508)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count