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This transgene consists of the CAG promoter , a loxP flanked EGFP reporter gene, the human papillomavirus 16 (HPV-16) E6 and E7 genes, an IRES, and the luciferase gene. In the absence of Cre recombinase, the EGFP is expressed and prevents the expression of HPV-16 and luciferase. When the floxed EGFP is removed via Cre-mediated recombination, expression of HPV and luciferase are induced. (J:210533)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
