A loxP site was inserted downstream of exon 1 and a floxed neo cassette was inserted downstream of exon 7 via homologous recombination. Cre mediated recombination removed the neo cassette. (J:215244)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count