The targeting vector contains a single loxP site upstream of exon 1 and a loxP-flanked puromycin cassette downstream of exon 4. Cre-mediated recombination removed the sequence between exons 1 and 4. (J:223572)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count