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A cDNA clone was produced using RNA purified from a confirmed alveolar soft part sarcoma tumor. The cDNA contained the ASPCR1/TFE3 fusion product of the t(X;17) chromosomal translocation typical of these tumors. This cDNA was inserted downstream of a floxed STOP sequence consisting of the neomycin resistance gene and a polyadenylation transcription termination sequence and upstream of an IRES-EGFP. Both the fusion gene and EGFP will be translated form the same transcript following cre-mediated recombination to remove the STOP. (J:217462)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
