A loxP site was inserted between exons 1 and 2. An FRT-flanked neomycin resistance cassette with a loxP site was inserted between exons 7 and 8. Flp-mediated recombination remove the selection cassette and left exons 2 through 7 floxed. (J:236223)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count