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The murine Kras containing the G12D mutation is under the control of the tet-operator with a lox-stop-lox cassette inserted between the promoter and the start codon of the Kras open reading frame. Expression of the mutant Kras is dependent on Cre-mediated deletion of the stop cassette. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:186194)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
