The transgene expressed EGFP under the control of a 4.8 kb mouse S100B promoter gene sequence located 5' to the translation initiation site. Several transgenic lines were generated, with lines 4, 9, and 11 displayed identical EGFP expression patterns. Line 11 displays the highest level of EGFP expression and was expanded and studied further. In adult mice, the highest level of EGFP expression was found in ependymocytes; astrocytes; and spinal, medullar, pontine, and deep cerebellar S100B neurons. (J:82129)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6N x DBA/2N)F1
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Insertion
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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