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A 180-kb YAC fragment containing the entire human MSR1 gene was used to generate transgenic mice expressing the gene under the control of the regulatory elements contained within the YAC. Two founder mice were shown to contain the complete sequence and were bred to generate two lines (lines 2 and 3). Line 3 expresses higher levels of the encoded protein and was expanded and studied further. (J:59667)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
