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Transgenic mice with inducible cardiomyocyte-specific expression of an N111G mutant form of the human angiotensin II (Ang II) type-1 receptor (hAT1R) showed strong cardiomyocyte-specific LacZ activation in both neonatal and adult hearts, and pulmonary veins when induced. When adults were given dox, the receptor expression was repressed. (J:162208)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
