Rearranged Valpha4.1 JalphaNEW and Vbeta1.1 Jbeta2.5 sequences are obtained from L-restricted CD3<+> CD4<-> CD8<+> cytotoxic T lymphocytes (clone 6C2), which recognizes an epitope located between residues 28-39 of HBsAg. These TCR sequences were cloned into TCR cassette expression vectors (pTalpha and pTbeta), and co-injected. The primary investigator indicates that cells from founder lines 16 and 36 exhibit no differences in epitope recognition. (J:213364)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
BALB/cByJ or C57BL/6J
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Insertion
--
--
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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