Rearranged Valpha4.1 JalphaNEW and Vbeta1.1 Jbeta2.5 sequences are obtained from L-restricted CD3<+> CD4<-> CD8<+> cytotoxic T lymphocytes (clone 6C2), which recognizes an epitope located between residues 28-39 of HBsAg. These TCR sequences were cloned into TCR cassette expression vectors (pTalpha and pTbeta), and co-injected. The primary investigator indicates that cells from founder lines 16 and 36 exhibit no differences in epitope recognition. (J:213364)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count