An HA-tagged form of human RASA1 fragment N bearing the D157A mutation (preventing it from being cleaved by caspases) is expressed under the control of the rat insulin promoter and regulatory sequences of the simian virus 40 (SV40) gene. Four independent RIP-Nexpressing founders were obtained (1, 2, 3 and 4). (J:154378)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count