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A human SP-C delta exon4 cDNA was generated by deleting nucleotides 325435 (adenosine of start ATG is base pair 1). A transgene construct was generated by subcloning the human SP-C delta exon4 cDNA into a vector containing the 13-kb mouse SP-C promoter, a rabbit globin intronic/exonic sequences, and a bovine growth hormone polyadenylation signal. Two founder mice were generated but did not survive. (J:87084)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
