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EN
S205D (AGT->GAT) and K224A (AAA->GCA) point mutations were introduced to the catalytic subunit of the gene and an FRT-flanked neomycin selection cassette was inserted in intron 6. The neomycin selection cassette was excised through crosses with Tg(ACTFLPe)9205Dym deleter mice, leaving a single FRT site in intron 6/7. (J:198414)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
