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The transgenic construct contains a mouse vav 1 oncogene promoter/control regions directing expression of a wildtype (catalytically-active) human eukaryotic translation initiation factor 2-alpha kinase 2 cDNA sequence (EIF2AK2). Three transgenic (TgPKR) founder lines were generated; all displaying the same phenotype and were used interchangeably. (J:196300)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
