Exons 2-6 flanked by two loxP sites and a Frt-flanked neo cassette before the second loxP site were inserted via homologous recombination. Cre-mediated recombination removed exons 2-6 and the neo-cassette. (J:217351)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count