Transgenic mouse line carrying 8 copies of a reporter tyrosinase construct (TYR5), described previously allowing pigmentation rescue of albino recipient strains and whose expression level is fully dependent on the site of integration and the number of copies of the mouse line. This line expresses intermediate TYR5 levels, resulting in pigmented eyes and grey uniform coat color pigmentation. (J:185183)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Hsd:NMRI
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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