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This is a Cre-dependent allele that conditionally expresses a SNAP-tag protein containing a membrane associated CaaX consensus sequence. The SNAP-tag construct consists of an engineered O6-alkylguanine-DNA alkyltransferase that can be specifically and irreversibly labeled with O6-benzylguanine (BG) derivatives. Cre-mediated removal of the stop cassette induces expression of the SNAP-CaaX protein. The Cre-dependent conditional expression of SNAPCaax inner membrane protein allows chemical labelling of proteins in specific cell types in vivo. (J:222844)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
