A transgenic mouse cDNA construct encoding the signal sequence and C-terminal endostatin part of the type alpha1(XVIII) chain was expressed under the control of the human K14 promoter. Three transgenic founders, K18, G20, and J4, were obtained. Expression in line J4 was the strongest and was studied further. (J:95251)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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