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The entire human gene, including the 5' and 3' flanking regions was used to create transgenic mice. Expression patterns were comparable to the endogenous mouse gene, with the highest levels seen in lymphoid tissues, liver, and lung. Three transgenic lines were generated (TgE1322, TgE1334, and TgE1335) carrying various transgene copy numbers. (J:114744)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
