The transgene contains a duplex of CAGC1/2 sequences and a duplex of SMAD binding elements 2 and 3 (Bmp-responsive element; BRE) derived from the mouse Id1 gene upstream of an Hspa1a minimal promoter that drive expression of the lacZ reporter gene followed by an SV40 polyadenylation sequence. Lines 1C10 and 2F3 were generated. (J:142745)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
--
Insertion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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