Exons 4 and 5 were floxed and an Frt flanked neo cassette was inserted in intron 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:213781)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count