The codon optimized icre and an FRT-flanked neomycin resistance cassette were inserted into exon 1 upstream of the translation initiation site of mouse Edn2. Flp-mediated recombination removed the selection cassette. Lines 9 and 12 were generated. (J:218893)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count