A conditional-ready gene trap cassette with F3, Frt, LoxP, and Lox511 sites flanking a beta-geo reporter was inserted into exon 1 and subsequent breeding to a Flp-deleter yielded this allele in which the insertion is in inverse orientation on the negative strand so transcription is normal and the insertion is still subject to Cre-mediated re-inversion. (J:236978)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
6
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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