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A neomycin resistance cassette replaced the first three coding exons. Western blot analysis revealed a truncated immunoreactive product in the brains of P0 homozygous mutant pups that decreased after P7 and was not detectable in adult mice. Immunofluorescence analysis confirmed the absence of protein expression in adult mutant brains. (J:221234)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
