A targeting vector was designed to insert (from 5 to 3) a CAG promoter, a frt-flanked CreERT2 (Cre recombinase fused to an estrogen receptor ligand binding domain) coding sequence, and an attB/attP-flanked neomycin (neo) resistance cassette downstream of the collagen A1 (Col1a1) promoter. PhiC31-mediated recombination removed the neo cassette. (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion
--
1
24
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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