The transgenic construct contains a full length human dystrophin gene modified by the deletion of repeat 4 through repeat 19 and the C-terminus to generate a micro-dystrophin cDNA under the control of the rat cardiac muscle specific alpha myosin (Myh6 or alpha-MHC) promoter. Founder lines 24 and 25 were combined. (J:94077)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count