A lacZ cassette with a 5' loxP site and a polyadenylation sequence was inserted at the translation initiation site in exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Immunohistochemistry confirmed the absence of protein expression in skin and stomach at E18.5. (J:218441)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count