Log In|Sign Up
EN
A floxed STOP cassette was inserted upstream of a modified exon 1 in which an Esr1 cDNA is fused to the coding sequence with the nucleotide susbtitution that results in the amino acid substitution of glycine with aspartic acid at position 12 (p.G12D). Flp-mediated recombination removed an FRT site flanked neomycin resistance cassette inserted downstream of the modified exon 1. (J:220921)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
