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These transgenic mice express a rat Igf cDNA driven by the mouse alpha-myosin heavy chain (alpha-MHC) promoter to restrict expression of Igf1 to the mouse myocardium. Three founder lines were created (F010, F022, and F018), and a single transgenic line was kept for further analysis (F018). (J:137808)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
