Exons 7 and 8 were floxed by two LoxP sequences, followed by a frt-neo-frt cassette in intron 8. Floxed exons 7 and 8 and the neo cassette were then removed. Western analysis confirmed the absence of expression. (J:219040)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count