Log In|Sign Up
EN
A targeting vector containing an FRT-flanked PGK-NEO cassette, a DTA cassette and a Cre recombinase cassette are used to replace the start codon in exon 1 and 59 bp of signal peptide sequence at the ATG start codon. Flp-mediated recombination removed the FRT-flanked neo cassette. Immunostaining analysis of the suprachiasmatic nucleus does not detect a gene product. The investigator reports that the Cre recombinase cassette is non-functional or very minimally functional. (J:219926)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
