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Recombinase mediated cassette exchange (RMCE) on KH2 cells, which contain Gt(ROSA)26Sortm1(rtTA*M2)Jae and an FRT-flanked PGK-Neo-pA in the 3' UTR of the Col1a1 gene, replaced the FRT-flanked neo cassette with a cassette that contains the tetracycline promoter, an EGFP gene and a short hairpin sequence targeting Pten (shPten.1522). (J:212919)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
