LoxP sites are inserted within the first coding exon 5' of the initiator methionine codon, and 3' of an SV40 polyadenylation signal that is inserted immediately 3' of the 3' UTR. The following is downstream of the 3' loxP site: the coding region for human placental alkaline phosphatase (AP), and an FRT-flanked phosphoglycerate kinase (PGK)-Neo cassette (FNF). (J:264733)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count