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EN
A guanine to adenine at position 3925 (ATC>GTC) and adenine at position 3977 instead of guanine (CGT>CAT) were introduced in exon 28 to create the I1309V and R1325H mutations. In addition, a floxed pGK-Neo cassette was inserted downstream of exon 28 which was removed via cre-mediated excision. (J:220792)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
