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EN
Exons 3 and 4 were replaced with modified exons in which nucleotide substitution result in the amino acid substitutions of phenylalanine for tyrosine at positions 120 and 127 (Y120F, Y127F). Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette with a 5' loxP site inserted between the modified exons. An additional loxP site is located downstream of exon 4. (J:212410)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
