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The human ALK cDNA with the F1174L mutation is under the control of the rat tyrosine hydroxylase promoter, which drives expression in committed sympathetic precursor cells of the neural crest. Four lines were established; 1, 2, 3, and 4. Line 2 is entered as a representative line. (J:191012)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
