A transgenic construct containing a wild-type mouse minigene under the control of the Pb prostate-specific promoter consisting of two androgen response elements from the rat probasin gene promoter arranged sequentially. The full-length wild-type minigene consists of genomic DNA sequence of the first 3 exons and introns, and cDNA sequence encoding exons 4 though 19. Founder line B was subsequently established. (J:178109)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count